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Description
Ephrin-A1 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms EFNA1, LERK 1, TNFAIP4, EPLG1, B61, ECKLG, EFL1 Accession P20827 1 Amino Acid Sequence Asp19 Ser182, with hIgG Fc Expression System HEK293 Molecular Weight 51 55 kDa (R) Purity 95% by SDS PAGE & RP HPLC Conjugation Unconjugated Physical Appearance Lyophilized Powder Storage Buffer PBS, PH7. 4, 5% trehalose Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid
Product Specification
| Species | Human |
| Synonyms | EFNA1, LERK-1, TNFAIP4, EPLG1, B61, ECKLG, EFL1 |
| Accession | P20827-1 |
| Amino Acid Sequence | Asp19-Ser182, with hIgG Fc |
| Expression System | HEK293 |
| Molecular Weight | 51-55 kDa (R) |
| Purity | ＞95% by SDS-PAGE & RP-HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage |
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1.Singh PK, Rybak JA, Schuck RJ, Barrera FN, Smith AW. Phosphatidylinositol (4,5)-bisphosphate drives the formation of EGFR and EphA2 complexes. bioRxiv [Preprint]. 2024 May 4:2024.05.03.592400. PMID: 38746348; |
Background
Ephrin-A1 (EFNA1) is also known as EPLG1, LERK1, TNFAIP4, Immediate early response protein B61, which belongs to the ephrin family. EFNA1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA1 is cell surface GPI-bound ligand for Eph receptors, and is a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.
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